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Methaqualone, a quinazoline derivative was first synthesized in 1951, and used medically as a hypnotic for the short-term treatment of insomnia, and also as a recreational drug. It acts as a central nervous system depressant similarly to barbiturates. In prescribed doses, Quaaludes promotes relaxation, sleepiness, and sometimes a feeling of euphoria. It causes a drop in blood pressure and slows the pulse rate. These properties are the reason why it was initially thought to be a useful sedative and anxiolytic.
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